Description

Phenol, 5-Isothiocyanato-2-Methyl- (9Ci) is a specialized phenolic derivative featuring a reactive isothiocyanate functional group. This compound serves as a critical building block and derivatization agent in advanced organic synthesis, enabling the introduction of thiourea linkages. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical sectors for creating novel active ingredients and intermediates. Its unique structure makes it valuable for targeted molecular modifications and bioconjugation strategies.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme pathways.
• Agrochemical Research: Used in developing new herbicides, fungicides, and plant growth regulators with enhanced activity.
• Bioconjugation Reagent: Employed for labeling proteins, peptides, and antibodies due to its reactive isothiocyanate group, which binds to amine groups.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialty polymers and resins with tailored properties.
• Chemical Biology Probes: Utilized in the design of activity-based probes for studying biological processes and target identification.
• Dye and Pigment Synthesis: Intermediate in the manufacture of specialized colorants and imaging agents.

Basic Information

Item	Detail
Product Name	Phenol, 5-Isothiocyanato-2-Methyl- (9Ci)
CAS No.	352439-89-5
Molecular Formula	C8H5NOS
Molecular Weight	163.20 g/mol
Synonyms	5-Isothiocyanato-2-methylphenol; 2-Methyl-5-isothiocyanatophenol; 2-Hydroxy-4-methylphenyl isothiocyanate; 4-Methyl-2-hydroxyphenyl isothiocyanate; NSC 405124; Phenol, 5-isothiocyanato-2-methyl-; 5-Isothiocyanato-o-cresol
EINECS	Contact for details

Quality Control

Our Phenol, 5-Isothiocyanato-2-Methyl- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. For custom purity grades or specific impurity profiles, please contact our technical team.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.