Description

4-(1H-Pyrazol-1-Yl)Phenyl Isothiocyanate is a specialized organic building block featuring a reactive isothiocyanate group linked to a phenylpyrazole scaffold. This compound matters as a versatile intermediate for constructing heterocyclic compounds and functional materials, enabling the synthesis of novel pharmacophores and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for lead optimization and the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in kinase inhibitor and anticancer agent research.
• Agrochemical Synthesis: Used in the creation of new herbicides, fungicides, and insecticides with enhanced efficacy.
• Chemical Biology Probe: Serves as a reactive handle for bioconjugation and labeling of proteins or other biomolecules due to the isothiocyanate group.
• Material Science Precursor: Employed in the synthesis of advanced polymers, liquid crystals, and organic electronic materials.
• Research & Development: A valuable tool for academic and industrial research in organic and medicinal chemistry for exploring new chemical spaces.
• Custom Synthesis: Serves as a starting point for contract research organizations (CROs) and CDMOs for client-specific molecule development.

Basic Information

Product Name	4-(1H-Pyrazol-1-Yl)Phenyl Isothiocyanate
CAS No.	352018-96-3
Molecular Formula	C10H7N3S
Molecular Weight	201.25 g/mol
Synonyms	1-(4-Isothiocyanatophenyl)-1H-pyrazole; 4-(1H-Pyrazol-1-yl)phenyl isothiocyanate; 4-Pyrazol-1-ylphenyl isothiocyanate; p-(1H-Pyrazol-1-yl)phenyl isothiocyanate; 4-(Pyrazol-1-yl)phenyl isothiocyanate; [4-(1H-Pyrazol-1-yl)phenyl] isothiocyanate; 1-(4-Isothiocyanato-phenyl)-1H-pyrazole
EINECS	Contact for details

Quality Control

Our 4-(1H-Pyrazol-1-Yl)Phenyl Isothiocyanate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality assurance supports your research and development needs with reliable, high-purity materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.