Description

tert-Butyl n-(5-Isothiocyanatopentyl)Carbamate is a specialized bifunctional organic compound that serves as a critical intermediate in advanced chemical synthesis. Its molecular structure, featuring both a protected amine (Boc group) and a reactive isothiocyanate moiety, makes it a versatile building block for constructing complex molecules with high precision. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, diagnostic agents, and biochemical probes.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for targeted therapies.
• Bioconjugation & Probe Synthesis: Used to label peptides, proteins, and antibodies with fluorescent or affinity tags for diagnostic and research applications.
• Peptidomimetic & Drug Discovery: Enables the introduction of thiourea linkages and functionalized side chains in medicinal chemistry programs.
• Chemical Biology Tool: Facilitates the study of protein-protein interactions and cellular pathways through site-specific modification.
• Material Science: Potential monomer or cross-linker for creating functional polymers with specific chemical handles.

Basic Information

Product Name	tert-Butyl n-(5-Isothiocyanatopentyl)Carbamate
CAS No.	347890-46-4
Molecular Formula	C11H20N2O2S
Molecular Weight	244.35 g/mol
Synonyms	5-Isothiocyanato-1-(tert-butoxycarbonylamino)pentane; 1-Boc-amino-5-isothiocyanatopentane; Boc-NH-(CH2)5-NCS; N-Boc-1,5-diaminopentane isothiocyanate; N-(5-Isothiocyanatopentyl)carbamic acid tert-butyl ester; tert-Butyl (5-isothiocyanatopentyl)carbamate; N-Boc-1,5-pentanediamine isothiocyanate
EINECS	Contact for details

Quality Control

Our tert-Butyl n-(5-Isothiocyanatopentyl)Carbamate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.