Description

1H-Pyrrole-2-Carboxylic Acid, 5-(Chlorocarbonyl)-, Methyl Ester (9Ci) is a high-purity, multifunctional chemical building block with the CAS number 347362-31-6. This compound is valued for its reactive chlorocarbonyl and ester groups, making it a versatile intermediate for constructing complex heterocyclic systems. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of pyrrole-based drug candidates, including potential kinase inhibitors and antimicrobial agents.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides with heterocyclic cores.
• Material Science Research: Serves as a precursor for functionalized polymers, dyes, and organic electronic materials.
• Chemical Biology: Employed in the development of molecular probes and bioconjugates due to its reactive handles.
• Custom Synthesis: A critical starting material for contract research organizations (CROs) and CDMOs producing bespoke fine chemicals.

Basic Information

Product Name	1H-Pyrrole-2-Carboxylic Acid, 5-(Chlorocarbonyl)-, Methyl Ester (9Ci)
CAS No.	347362-31-6
Molecular Formula	C7H6ClNO3
Molecular Weight	187.58 g/mol
Synonyms	Methyl 5-(chlorocarbonyl)-1H-pyrrole-2-carboxylate; 5-(Chlorocarbonyl)-1H-pyrrole-2-carboxylic acid methyl ester; 1H-Pyrrole-2-carboxylic acid, 5-(chlorocarbonyl)-, methyl ester; Methyl 5-chloroformylpyrrole-2-carboxylate; Pyrrole-2,5-dicarboxylic acid 2-methyl ester 5-acid chloride
EINECS	Contact for details

Quality Control

Our 1H-Pyrrole-2-Carboxylate derivative is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the stringent requirements of research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.