Description

2-Fluoro-5-(Trifluoromethoxy)Benzyl Alcohol CAS NO 344411-08-1 is a high-value fluorinated aromatic building block characterized by its benzyl alcohol functionality and trifluoromethoxy substituent. This compound is critical for introducing specific fluorine-containing motifs into target molecules, enhancing their metabolic stability, lipophilicity, and binding affinity. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of advanced intermediates and active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in oncology, CNS, and antiviral research.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides where the fluorine atoms improve biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated compounds for electronic display applications.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, esterifications, and etherifications to construct complex molecular architectures.
• Material Science Research: Utilized in the development of specialty polymers and coatings with unique surface properties.

Basic Information

Product Name	2-Fluoro-5-(Trifluoromethoxy)Benzyl Alcohol
CAS No.	344411-08-1
Molecular Formula	C8H6F4O2
Molecular Weight	210.13 g/mol
Synonyms	(2-Fluoro-5-(trifluoromethoxy)phenyl)methanol; 2-Fluoro-α-(trifluoromethoxy)benzenemethanol; 1-(2-Fluoro-5-(trifluoromethoxy)phenyl)methanol; 2-Fluoro-5-(trifluoromethoxy)benzenemethanol; 2-Fluoro-5-(trifluoromethoxy)benzylalcohol; α-Fluoro-α'-(trifluoromethoxy)benzyl Alcohol
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-(Trifluoromethoxy)Benzyl Alcohol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere for long-term storage. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.