Description

2-Oxazolecarbonyl Chloride, 4,5-Dimethyl- (9Ci) is a highly reactive heterocyclic acid chloride derivative, serving as a critical building block for the synthesis of complex organic molecules. Its value lies in enabling efficient amide bond formation and the introduction of the 4,5-dimethyloxazole moiety, a privileged scaffold in medicinal chemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those containing oxazole heterocycles.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides.
• Material Science: Precursor for functional polymers and advanced organic materials with specific electronic or optical properties.
• Peptide Mimetics & Bioconjugation: Facilitates the creation of peptide analogs and the labeling of biomolecules for research and diagnostic applications.
• Ligand & Catalyst Development: Employed in the synthesis of specialized ligands for metal catalysis and organocatalysts.
• Custom Synthesis & Contract Manufacturing: A vital reagent for fine chemical and custom synthesis houses serving diverse R&D projects.

Basic Information

Product Name	2-Oxazolecarbonyl Chloride, 4,5-Dimethyl- (9Ci)
CAS No.	344399-17-3
Molecular Formula	C6H6ClNO2
Molecular Weight	159.57 g/mol
Synonyms	4,5-Dimethyl-1,3-oxazole-2-carbonyl chloride; 4,5-Dimethyloxazole-2-carbonyl chloride; 2-Carbonyl chloride-4,5-dimethyloxazole; 4,5-Dimethyl-2-oxazolecarbonyl chloride; 4,5-Dimethyloxazole-2-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Every batch of 2-Oxazolecarbonyl Chloride, 4,5-Dimethyl- (9Ci) is produced and tested under stringent quality management protocols to ensure consistency and reliability for your synthetic processes. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity, identity, and impurity profiles. Our quality systems are designed to support cGMP-compliant applications where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.