Description

1-Piperidinecarbonyl Chloride, 2-(Hydroxymethyl)- (9Ci) is a specialized organic building block featuring both a reactive acid chloride group and a hydroxymethyl substituent on the piperidine ring. This bifunctional nature makes it a valuable intermediate for the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists working on new active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel piperidine-based drug candidates, including potential central nervous system (CNS) agents and enzyme inhibitors.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where the piperidine scaffold imparts specific biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating sophisticated ligands used in asymmetric catalysis and metal complexation.
• Polymer Modification: The reactive groups allow for incorporation into polymer backbones to create specialty polymers with tailored properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: An essential building block for custom synthesis houses serving the pharmaceutical and biotechnology industries.

Basic Information

Product Name	1-Piperidinecarbonyl Chloride, 2-(Hydroxymethyl)- (9Ci)
CAS No.	344326-76-7
Molecular Formula	C7H12ClNO2
Molecular Weight	177.63 g/mol
Synonyms	2-(Hydroxymethyl)piperidine-1-carbonyl chloride; 2-(Hydroxymethyl)-1-piperidinecarbonyl chloride; (2-Hydroxymethylpiperidino)carbonyl chloride; 1-Carboxy-2-hydroxymethylpiperidine chloride; Piperidine-1-carbonyl chloride, 2-(hydroxymethyl)-; 344326-76-7; 2-(Hydroxymethyl)piperidine-1-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 1-Piperidinecarbonyl Chloride, 2-(Hydroxymethyl)- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality parameters. Our commitment to cGMP principles and stringent in-process controls guarantees batch-to-batch consistency for your critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.