Description

1-Piperidinecarbonyl Chloride, 3-(Hydroxymethyl)- (9Ci) is a versatile and highly reactive organic intermediate, specifically a functionalized acid chloride derivative of piperidine. This compound is a critical building block in synthetic organic chemistry, enabling the efficient introduction of the piperidinecarbonyl moiety into target molecules. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting the central nervous system (CNS) and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides where the piperidine scaffold imparts specific biological activity.
• Peptide Mimetics & Drug Discovery: Serves as a valuable reagent for creating peptide analogs and other bioactive molecules in medicinal chemistry and high-throughput screening libraries.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development and the synthesis of novel chemical entities for various applications.
• Ligand & Catalyst Preparation: Useful for the functionalization of ligands and the preparation of specialized catalysts used in asymmetric synthesis.

Basic Information

Product Name	1-Piperidinecarbonyl Chloride, 3-(Hydroxymethyl)- (9Ci)
CAS No.	344326-73-4
Molecular Formula	C7H12ClNO2
Molecular Weight	177.63 g/mol
Synonyms	3-(Hydroxymethyl)piperidine-1-carbonyl chloride; 3-(Hydroxymethyl)-1-piperidinecarbonyl chloride; 1-Piperidinecarbonyl chloride, 3-(hydroxymethyl)-; (3-Hydroxymethyl-piperidin-1-yl)-carboxylic acid chloride; 3-Piperidinemethanol, 1-chlorocarbonyl-; 1-Chlorocarbonyl-3-piperidinemethanol
EINECS	Contact for details

Quality Control

Our 1-Piperidinecarbonyl Chloride, 3-(Hydroxymethyl)- is produced under strict quality control protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including HPLC, GC, and NMR for comprehensive characterization. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.