Description

1H-Pyrrole-2-Carbonylchloride,1-Methyl-5-(2-Oxopropyl)-(9Ci) is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key acyl chloride intermediate, enabling the efficient introduction of functionalized pyrrole moieties into complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing specific receptor binding profiles.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where the pyrrole scaffold can contribute to unique modes of action.
• Material Science Research: Acts as a monomer or functionalization agent in the creation of specialized polymers and organic electronic materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function or cellular pathways.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for fine chemical manufacturers offering bespoke synthesis services to clients in life sciences.

Basic Information

Product Name	1H-Pyrrole-2-Carbonylchloride,1-Methyl-5-(2-Oxopropyl)-(9Ci)
CAS No.	344298-53-9
Molecular Formula	C9H10ClNO2
Molecular Weight	199.63 g/mol
Synonyms	1-Methyl-5-(2-oxopropyl)-1H-pyrrole-2-carbonyl chloride; 1-Methyl-5-(2-oxopropyl)pyrrole-2-carboxylic acid chloride; 1-Methyl-5-acetonyl-1H-pyrrole-2-carbonyl chloride; 5-Acetonyl-1-methyl-1H-pyrrole-2-carbonyl chloride; 1-Methyl-5-(2-oxopropyl)-2-pyrrolecarbonyl chloride; (1-Methyl-5-(2-oxopropyl)-1H-pyrrol-2-yl)methanoyl chloride
EINECS	Contact for details

Quality Control

Our 1H-Pyrrole-2-Carbonylchloride,1-Methyl-5-(2-Oxopropyl)-(9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation by atmospheric moisture.

Specification

Item	Specification
Appearance	Light yellow to brown liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical 97-98%)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.