Description

4-Thiazolidinecarbonyl Chloride (9Ci) is a versatile and highly reactive organic intermediate, primarily used as a key building block in sophisticated chemical synthesis. Its value lies in its ability to introduce the 4-thiazolidinecarbonyl moiety, a crucial structural feature in various biologically active molecules. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced material sectors seeking to develop novel compounds with specific functionalities.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system disorders, infectious diseases, and metabolic conditions.
• Agrochemical Synthesis: Used in the research and development of new pesticides, herbicides, and fungicides, where the thiazolidine ring can contribute to biological activity.
• Peptide Mimetics & Bioconjugation: Acts as a reactive handle for modifying peptides or creating peptide-like structures (peptidomimetics) to enhance stability or bioavailability.
• Material Science Research: Employed in the development of specialized polymers, ligands for catalysis, or functionalized surfaces with specific chemical properties.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme function or protein-protein interactions within biological systems.

Basic Information

Product Name	4-Thiazolidinecarbonyl Chloride (9Ci)
CAS No.	344240-92-2
Molecular Formula	C4H4ClNOS
Molecular Weight	149.60 g/mol
Synonyms	4-Thiazolidinecarbonyl chloride; Thiazolidine-4-carbonyl chloride; 4-Carboxythiazolidine chloride; 1,3-Thiazolidine-4-carbonyl chloride; 4-Thiazolidine carboxylic acid chloride; (Thiazolidin-4-yl)carbonyl chloride; 4-Thiazolidinecarbonylchloride; 4-Thiazolidinecarboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 4-Thiazolidinecarbonyl Chloride is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and process development. A detailed Certificate of Analysis (COA) documenting purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	95.0 - 102.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.