Description

Cci 779 is a potent and selective small-molecule inhibitor of the mammalian target of rapamycin (mTOR) kinase. This compound is a critical research tool and pharmaceutical intermediate for investigating and developing targeted cancer therapies. It is primarily utilized by pharmaceutical R&D departments, academic research institutions, and biotechnology companies focused on oncology, immunology, and metabolic disease research.

Application

• Pharmaceutical Research & Development: As a key reference standard and active pharmaceutical ingredient (API) intermediate in the development of mTOR-targeted oncology therapeutics.
• Biochemical & Cell-Based Assays: Used to study mTOR signaling pathways, cellular proliferation, autophagy, and angiogenesis in various cancer cell lines.
• Preclinical Studies: Employed in animal models to evaluate the efficacy and pharmacokinetics of mTOR inhibition for treating solid tumors and other proliferative diseases.
• Mechanism of Action (MoA) Studies: A vital tool for elucidating the role of the PI3K/Akt/mTOR pathway in disease progression and drug resistance.
• Chemical Synthesis: Serves as a sophisticated building block for the synthesis of novel analogs and prodrugs with potential improved pharmacological profiles.

Basic Information

Product Name	Cci 779
CAS No.	343261-52-9
Molecular Formula	C56H87NO16
Molecular Weight	1030.28 g/mol
Synonyms	Temsirolimus; Torisel; CCI-779; 42-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate]rapamycin; NSC 683864; RAD 001 metabolite; mTOR Kinase Inhibitor CCI-779
EINECS	Contact for details

Quality Control

Our Cci 779 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and MS, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccant and inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.