Description

1-Cyclopropylmethyl-Pyrrolidine-2-Carboxylic Acid Hydrochloride is a high-purity, pharmaceutically relevant intermediate in its stable hydrochloride salt form. This compound matters as a critical building block for medicinal chemistry research and the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key synthon for the development of new drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs.
• Peptidomimetic Synthesis: Serves as a constrained proline analog for creating novel peptide-like molecules with enhanced metabolic stability.
• Agrochemical Development: Potential intermediate in the synthesis of advanced crop protection agents.
• Chemical Biology Probes: Useful for designing and synthesizing molecular probes to study biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for scale-up and GMP production of client-specific target molecules.

Basic Information

Product Name	1-Cyclopropylmethyl-Pyrrolidine-2-Carboxylic Acid Hydrochloride
CAS No.	342793-01-5
Molecular Formula	C10H17NO2 • HCl
Molecular Weight	219.71 g/mol
Synonyms	1-(Cyclopropylmethyl)-L-proline hydrochloride; (S)-1-(Cyclopropylmethyl)pyrrolidine-2-carboxylic acid hydrochloride; L-Proline, 1-(cyclopropylmethyl)-, hydrochloride; 1-Cyclopropylmethylproline HCl; Cyclopropylmethyl-proline hydrochloride; 2-Pyrrolidinecarboxylic acid, 1-(cyclopropylmethyl)-, hydrochloride, (2S)-; 342793-01-5
EINECS	Contact for details

Quality Control

Our 1-Cyclopropylmethyl-Pyrrolidine-2-Carboxylic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting cGMP and ISO standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Purity (HPLC, Area%)	≥99.0%
Optical Rotation	Contact for details
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.