Description

3-Pyridinecarbonyl Chloride, 2-Amino- (9Ci) is a versatile and highly reactive heterocyclic building block, primarily used as a key intermediate in advanced organic synthesis. Its value lies in its bifunctional nature, featuring both an amino group and an acid chloride moiety, which enables the efficient construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug molecules, particularly those targeting neurological and oncological pathways.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials with specific electronic or photonic properties.
• Chemical Biology Probes: Utilized to create labeled compounds and molecular probes for studying biological processes and enzyme inhibition.
• Custom Synthesis and R&D: A valuable reagent for contract research organizations (CROs) and academic laboratories engaged in novel heterocyclic chemistry.

Basic Information

Item	Detail
Product Name	3-Pyridinecarbonyl Chloride, 2-Amino- (9Ci)
CAS No.	342614-83-9
Molecular Formula	C6H5ClN2O
Molecular Weight	156.57 g/mol
Synonyms	2-Aminonicotinoyl chloride; 2-Aminopyridine-3-carbonyl chloride; 2-Amino-3-pyridinecarbonyl chloride; 3-Carbonyl chloride-2-aminopyridine; 2-Amino-3-pyridinylcarbonyl chloride; 2-Aminonicotinic acid chloride; 2-Aminopyridine-3-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 3-Pyridinecarbonyl Chloride, 2-Amino- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistent chemical identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring reliable and traceable raw materials for GMP or research-grade synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.