Description

Oxamflatin (CAS NO 342373-23-3) is a potent and selective small molecule inhibitor of histone deacetylase (HDAC) enzymes, specifically targeting Class I HDACs. This compound is a critical research tool for investigating epigenetic regulation, cellular differentiation, and gene expression in various disease models. It is primarily utilized by researchers and developers in the pharmaceutical and biotechnology sectors for drug discovery, target validation, and preclinical studies in oncology and neurology.

Application

• Biomedical Research: Used as a reference standard and active compound in epigenetic and cancer biology studies.
• Drug Discovery & Development: Serves as a lead compound or pharmacophore for designing novel HDAC inhibitors.
• Cell Biology Studies: Applied in *in vitro* assays to study the effects of HDAC inhibition on cell cycle, apoptosis, and differentiation.
• Neuroscience Research: Investigated for its potential neuroprotective or neurodegenerative effects in models of CNS disorders.
• Biochemical Assays: Employed in enzymatic assays to determine HDAC activity and inhibitor potency (IC50).
• Academic & Institutional Research: A key reagent for universities and research institutes exploring chromatin remodeling and gene silencing mechanisms.

Basic Information

Product Name	Oxamflatin
CAS No.	342373-23-3
Molecular Formula	C₁₄H₁₈N₂O₃
Molecular Weight	262.31 g/mol
Synonyms	N-Hydroxy-4-[[(2S)-2-(phenylmethyl)-3-(phenylsulfonyl)propanoyl]amino]benzamide; Oxamflatin; [4-[[(2S)-2-Benzyl-3-(phenylsulfonyl)-1-oxopropyl]amino]phenyl]-hydroxymethyl ketone; HDAC Inhibitor, Oxamflatin; (2S)-2-Benzyl-N-[4-(hydroxycarbamoyl)phenyl]-3-(phenylsulfonyl)propanamide
EINECS	Contact for details

Quality Control

Our Oxamflatin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with research-grade specifications. We support cGMP-compliant production for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. Due to its hygroscopic nature, the container must be kept tightly sealed in a desiccated environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.