Description

Propanoyl Bromide, 2,3-Dioxo- is a highly reactive and versatile acyl bromide derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its ability to efficiently introduce the 2,3-dioxopropanoyl functional group, enabling the construction of complex heterocyclic and pharmaceutical intermediates. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity, specialized reagents for innovative synthesis.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for constructing active pharmaceutical ingredients (APIs), particularly those containing diketone or heterocyclic motifs.
• Agrochemical Development: Used in the synthesis of novel herbicides, fungicides, and insecticides that require specific acylating agents.
• Fine Chemical Manufacturing: Employed in the production of specialty chemicals, dyes, and complex organic molecules for research and industrial applications.
• Academic & Industrial R&D: A valuable tool in method development and exploratory chemistry for creating new carbon-carbon and carbon-heteroatom bonds.
• Peptide Mimetic & Prodrug Synthesis: Facilitates the introduction of ketone-based functional groups used in the design of peptide analogs and prodrug linkers.
• Material Science Precursor: Acts as a starting material for synthesizing organic ligands and monomers for advanced polymeric materials.

Basic Information

Product Name	Propanoyl Bromide, 2,3-Dioxo-
CAS No.	340171-61-1
Molecular Formula	C3H3BrO3
Molecular Weight	166.96 g/mol
Synonyms	2,3-Dioxopropanoyl Bromide; 3-Bromo-2,3-dioxopropanoic Acid; Oxalyl Bromide, Methyl-; α-Ketopropanoyl Bromide; Pyruvoyl Bromide; 3-Bromo-2,3-dioxopropanoic Acid Bromide; Bromo(dioxo)propanoic Acid; Propanoyl bromide, 2,3-dioxo- (9CI)
EINECS	Contact for details

Quality Control

Every batch of Propanoyl Bromide, 2,3-Dioxo- is manufactured and tested under strict quality management systems to ensure consistency and reliability for your critical applications. Our products undergo rigorous analytical testing, including HPLC, NMR, and titration methods, to confirm identity, purity, and absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Impurities (HPLC)	≤ 2.0% (total)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.