Description

(-)-Ouabain Hydrate 98 is a high-purity, plant-derived cardiac glycoside and a potent, selective inhibitor of the Na⁺/K⁺-ATPase enzyme. This compound is a critical research tool for studying ion transport mechanisms, cellular signaling pathways, and cardiac physiology. It is essential for researchers and developers in the fields of pharmacology, biochemistry, and cardiovascular disease research, where precise biological activity is required.

Application

• Biochemical Research: As a standard and specific inhibitor for studying Na⁺/K⁺-ATPase function and ion pump kinetics in vitro.
• Pharmacological Studies: Used in cell-based assays and animal models to investigate cardiac contractility, hypertension, and digitalis-like effects.
• Signal Transduction Research: Employed to explore the role of Na⁺/K⁺-ATPase as a signal transducer in cell growth, apoptosis, and hypertrophy.
• Reference Standard: Serves as a high-purity analytical standard for quality control in pharmaceutical development and academic research.
• Neuroscience: Applied in studies of neurotransmitter release and neuronal excitability where ion pump activity is a key factor.

Basic Information

Product Name	(-)-Ouabain Hydrate 98
CAS No.	340169-01-9
Molecular Formula	C₂₉H₄₄O₁₂ • xH₂O
Molecular Weight	728.70 g/mol (anhydrous basis)
Synonyms	Ouabain Octahydrate; G-Strophanthin; Acocantherin; Strophanthin G; 3β-[(2,6-Dideoxy-α-L-mannopyranosyl)oxy]-1β,5,11α,14,19-pentahydroxycard-20(22)-enolide Hydrate; (1β,3β,5β,11α)-19-[(2,6-Dideoxy-α-L-mannopyranosyl)oxy]-1,5,11,14-tetrahydroxycard-20(22)-enolide Hydrate
EINECS	Contact for details

Quality Control

Our (-)-Ouabain Hydrate 98 is manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and other critical parameters. We adhere to high standards suitable for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.