Description

1-(4-Fluorophenyl)Cyclobutanol is a versatile fluorinated cyclobutanol derivative, serving as a crucial synthetic intermediate in modern organic chemistry. Its value lies in the unique structural combination of the cyclobutyl ring and the fluorinated aromatic system, which is pivotal for modulating the physicochemical properties of target molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Used in the development of new herbicides and fungicides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated organic compounds used in electronic displays and optoelectronic devices.
• Chemical Biology Probe Synthesis: Employed to create molecular probes for studying enzyme mechanisms and protein-ligand interactions.
• Polymer Modification: Acts as a monomer or modifier to introduce fluorinated phenyl groups into polymer chains, altering material properties like hydrophobicity and thermal stability.
• Academic & Process Chemistry: Utilized in methodological studies and scale-up process optimization for complex organic syntheses.

Basic Information

Product Name	1-(4-Fluorophenyl)Cyclobutanol
CAS No.	339365-53-6
Molecular Formula	C10H11FO
Molecular Weight	166.19 g/mol
Synonyms	4-Fluorophenylcyclobutanol; 1-(4-Fluorophenyl)cyclobutan-1-ol; (4-Fluorophenyl)cyclobutanol; Cyclobutanol, 1-(4-fluorophenyl)-; α-(4-Fluorophenyl)cyclobutyl alcohol; p-Fluorophenylcyclobutanol; 339365-53-6; 1-(p-Fluorophenyl)cyclobutanol
EINECS	Contact for details

Quality Control

Our 1-(4-Fluorophenyl)Cyclobutanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP standards where applicable to support our clients' regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.