Description

3-(4-Fluoroanilino)-1-(2-Phenyl-1,3-Thiazol-5-Yl)-2-Propen-1-One is a specialized organic compound featuring a chalcone-like structure integrated with a fluorinated aniline and a phenylthiazole moiety. This molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active compounds targeting a range of therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting kinase inhibition or other protein-protein interactions.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new pharmacophores.
• Agrochemical Development: Serves as a precursor in the research and synthesis of new-generation pesticides and herbicides.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and target validation.
• Material Science Research: Investigated as a potential monomer or precursor for specialty polymers and organic electronic materials.
• Academic & Institutional R&D: Employed in university and research institute laboratories for fundamental organic synthesis and heterocyclic chemistry studies.

Basic Information

Product Name	3-(4-Fluoroanilino)-1-(2-Phenyl-1,3-Thiazol-5-Yl)-2-Propen-1-One
CAS No.	338414-54-3
Molecular Formula	C18H13FN2OS
Molecular Weight	324.37 g/mol
Synonyms	3-[(4-Fluorophenyl)amino]-1-(2-phenyl-1,3-thiazol-5-yl)prop-2-en-1-one; 1-(2-Phenyl-1,3-thiazol-5-yl)-3-[(4-fluorophenyl)amino]prop-2-en-1-one; (E)-3-((4-Fluorophenyl)amino)-1-(2-phenylthiazol-5-yl)prop-2-en-1-one; 338414-54-3; 5-(3-(4-Fluoroanilino)acryloyl)-2-phenylthiazole; Chalcone derivative bearing 4-fluoroanilino and 2-phenylthiazole
EINECS	Contact for details

Quality Control

Our 3-(4-Fluoroanilino)-1-(2-Phenyl-1,3-Thiazol-5-Yl)-2-Propen-1-One is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is supplied with every batch to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, especially after opening the original packaging. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.