Description

8-Nitro-D-Guanosine is a chemically modified nucleoside derivative, specifically a nitrated analog of guanosine. This compound is of significant interest in biochemical and pharmaceutical research due to its role as a key intermediate and building block. It is primarily utilized by researchers and developers in the fields of medicinal chemistry, nucleotide synthesis, and life science research for investigating nucleic acid modifications and developing novel therapeutic agents.

Application

• Medicinal Chemistry Research: Serves as a crucial intermediate in the synthesis of novel nucleoside analogs with potential antiviral or anticancer activity.
• Biochemical Probe Development: Used to study nucleic acid structure, function, and protein-nucleic acid interactions due to its modified base.
• Nucleotide Synthesis: Acts as a specialized building block for the preparation of modified oligonucleotides for diagnostic and research applications.
• Pharmaceutical Intermediate: Employed in the research and development pipeline for new drug candidates targeting various diseases.
• Academic & Institutional Research: Utilized in university and government laboratories for fundamental studies in chemical biology and organic synthesis.

Basic Information

Product Name	8-Nitro-D-Guanosine
CAS No.	337536-53-5
Molecular Formula	C10H12N6O7
Molecular Weight	328.24 g/mol
Synonyms	8-Nitro-guanosine; Guanosine, 8-nitro-; 8-Nitro-D-ribofuranosylguanine; 9-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-8-nitro-1,9-dihydro-6H-purin-6-one; 8-Nitro-9-β-D-ribofuranosylguanine; 8-Nitro-Guanosine; 8-Nitro-D-ribosylguanine
EINECS	Contact for details

Quality Control

Our 8-Nitro-D-Guanosine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) documenting identity, purity, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Water Content	≤ 5.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.