Description

2(1H)-Pyrimidinone, 4-Amino-1-[5-o-(1,3,4,5,5-Pentahydroxy-4-Methyl-1,3,5-Trioxido-2-Oxa-1,3,5-Triphosphapent-1-Yl)-β-D-Arabinofuranosyl]- is a sophisticated nucleoside analog with a unique triphosphate-mimicking side chain. This compound is of significant interest for its potential role as a biochemical tool and a key intermediate in advanced pharmaceutical research, particularly in the development of nucleotide-based therapeutics. It is primarily sought by research institutions and pharmaceutical companies engaged in antiviral, anticancer, and molecular biology applications.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel nucleotide analogs and prodrugs targeting viral polymerases.
• Antiviral Research: Investigated as a potential active pharmaceutical ingredient (API) or precursor in the development of treatments for viral infections.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving DNA/RNA polymerases and kinases.
• Oncology Research: Explored for its mechanism of action and incorporation into nucleic acids, making it relevant for anticancer drug discovery.
• Proteomics & Genomics: Serves as a specialized reagent in nucleotide labeling and sequencing technologies.
• Preclinical Development: Utilized in in vitro and in vivo studies to assess pharmacokinetics, metabolism, and efficacy of nucleotide-based candidates.

Basic Information

Product Name	2(1H)-Pyrimidinone, 4-Amino-1-[5-o-(1,3,4,5,5-Pentahydroxy-4-Methyl-1,3,5-Trioxido-2-Oxa-1,3,5-Triphosphapent-1-Yl)-β-D-Arabinofuranosyl]-
CAS No.	332863-86-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	4-Amino-1-((2R,3S,4R,5R)-3,4-dihydroxy-5-((((hydroxy(phosphonooxy)phosphoryl)oxy)(hydroxy)phosphoryl)oxy)methyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one; 1-(5-O-Phosphono-β-D-arabinofuranosyl)cytosine cyclic 3',5'-(hydrogen phosphate) P1-(4-amin-2-oxo-1(2H)-pyrimidinyl) ester; Cyclic CMP; cCMP; Arabinofuranosylcytosine cyclic phosphate; Nucleoside cyclic phosphate intermediate; cCMP analog
EINECS	Contact for details

Quality Control

Our production of this high-purity biochemical adheres to stringent quality systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and analytical data is provided with each shipment to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the sealed container to reach room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.