Description

Telatinib Mesylate is a potent and selective small-molecule inhibitor targeting key receptor tyrosine kinases involved in tumor angiogenesis and proliferation. This high-purity active pharmaceutical ingredient (API) is critical for pharmaceutical research and development, offering a valuable tool for studying cancer therapeutics. It is primarily utilized by pharmaceutical companies, biotechnology research firms, and academic institutions engaged in oncology drug discovery and preclinical studies. Telatinib Mesylate CAS NO 332013-26-0 represents a key intermediate for developing targeted cancer treatments.

Application

• Oncology Research & Drug Discovery: Primary use as a reference standard and active component in preclinical studies for various solid tumors.
• Biochemical Assay Development: Used as a specific inhibitor to study signaling pathways involving VEGFR, PDGFR, and c-Kit kinases.
• Pharmaceutical Intermediate: Serves as a critical raw material in the synthesis and formulation development of investigational new drugs (INDs).
• Academic & Institutional Research: Employed in university and research institute labs for mechanistic studies on angiogenesis and tumor growth.
• Contract Research Organization (CRO) Services: Supplied to CROs conducting client-sponsored pharmacology and toxicology testing.
• Analytical Method Development: Used as a certified reference material for developing and validating HPLC/LC-MS methods for quality control.

Basic Information

Product Name	Telatinib Mesylate
CAS No.	332013-26-0
Molecular Formula	C₃₀H₃₃N₇O₃S • CH₄O₃S
Molecular Weight	659.78 g/mol
Synonyms	Telatinib Mesylate; Telatinib methanesulfonate; BAY 57-9352; 6-[[5-[(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]-2-furanyl]methylene]-3-[(3S)-3-piperidinyl]-2,4(1H,3H)-pyrimidinedione methanesulfonate; 2,4(1H,3H)-Pyrimidinedione, 6-[[5-[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)methyl]-2-furanyl]methylene]-3-[(3S)-3-piperidinyl]-, monomethanesulfonate; BAY-57-9352; Telatinib (Mesylate)
EINECS	Contact for details

Quality Control

Our Telatinib Mesylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting high standards for pharmaceutical research. Certificates of Analysis (COA) detailing comprehensive test results, including assay by HPLC and related substance profiles, are provided with every shipment. We adhere to cGMP principles where applicable to support our clients' regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	Yellow to brownish solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single unknown impurity ≤0.5%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.