Description

Telatinib is a potent and selective small-molecule inhibitor targeting key tyrosine kinase receptors involved in tumor angiogenesis and proliferation. This compound is of significant interest for pharmaceutical research and development, particularly in the field of oncology. It is primarily utilized by research institutions, pharmaceutical companies, and CROs engaged in the discovery and preclinical evaluation of novel cancer therapeutics.

Application

• Oncology Research: Used as a reference standard or active pharmaceutical ingredient (API) in preclinical studies for various solid tumors.
• Kinase Profiling: Serves as a selective tool compound for studying the VEGFR, PDGFR, and c-Kit signaling pathways in cellular assays.
• Drug Discovery: A key intermediate or candidate in the development of novel multi-targeted tyrosine kinase inhibitor therapies.
• Biochemical Assays: Employed in high-throughput screening (HTS) and enzymatic assays to evaluate inhibition potency and mechanism of action.
• Formulation Development: Used in studies to develop stable dosage forms, such as tablets or capsules, for clinical trial materials.
• Pharmacology Studies: Applied in in vivo models to assess efficacy, pharmacokinetics, and toxicology profiles.

Basic Information

Product Name	Telatinib
CAS No.	332012-40-5
Molecular Formula	C₂₆H₂₉N₅O₃
Molecular Weight	459.54 g/mol
Synonyms	Telatinib; BAY 57-9352; 6-[[5-[(1,3-Benzodioxol-5-ylmethyl)amino]-2-pyrimidinyl]amino]-2,2-dimethyl-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one; BAY-57-9352; BAY 57 9352; BAY579352; UNII-2G6J5P5H8J
EINECS	Contact for details

Quality Control

Our Telatinib is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent controls for residual solvents and impurities. Certificates of Analysis (COA) with detailed chromatographic data are provided to ensure compliance with research-grade specifications and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.