Description

2-(6-Amino-9 H-Purin-8-Ylsulfanyl)-Propionic Acid is a specialized purine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular structure, which incorporates both a purine base and a propionic acid moiety, enabling its use in the development of novel pharmaceuticals and biochemical probes. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and life science sectors for applications in drug discovery and nucleotide chemistry.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel nucleoside analogs and purine-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a precursor or modifier in the development of enzyme inhibitors, receptor ligands, and fluorescent probes for cellular studies.
• Agrochemical Development: Serves as a synthetic intermediate in creating new crop protection agents and plant growth regulators.
• Nucleotide Chemistry: Employed in the modification of nucleic acids for antisense oligonucleotide and siRNA therapeutic research.
• Material Science: Potential monomer or additive in the synthesis of specialized polymers and functional materials.

Basic Information

Product Name	2-(6-Amino-9 H-Purin-8-Ylsulfanyl)-Propionic Acid
CAS No.	330983-00-1
Molecular Formula	C8H9N5O2S
Molecular Weight	239.26 g/mol
Synonyms	2-[(6-Amino-9H-purin-8-yl)thio]propanoic acid; 8-Mercaptoadenosine propionic acid derivative; 2-(6-Aminopurin-8-ylsulfanyl)propionic acid; 8-Thioadenine propionic acid analog; 2-(8-Mercapto-6-aminopurin-9-yl)propanoic acid; 6-Amino-8-mercaptopurine-2-propionic acid; 8-SH-Ade-PropAcid; NSC 760439
EINECS	Contact for details

Quality Control

Our production of 2-(6-Amino-9 H-Purin-8-Ylsulfanyl)-Propionic Acid adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity suitable for research and synthesis. We employ advanced analytical techniques, including HPLC, NMR, and mass spectrometry, for comprehensive characterization and impurity profiling. A Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with each shipment. Our quality system is designed to support applications requiring traceability and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.