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(R)-1-(2,6-Dichloro-3-Fluorophenyl)Ethanol CAS NO 330156-50-8
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CAS No.:330156-50-8
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
(R)-1-(2,6-Dichloro-3-Fluorophenyl)Ethanol is a high-purity chiral alcohol building block of significant importance in advanced organic synthesis. Its value lies in its role as a key intermediate for constructing complex molecules with defined stereochemistry, particularly in the pharmaceutical sector. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals where precise molecular architecture is critical.
Application
- Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
- Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides that require specific stereoisomers for optimal activity.
- Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
- Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances where enantiomeric purity is paramount.
- Academic and R&D: A valuable reagent for methodological studies in organic chemistry and process development in laboratory settings.
Basic Information
| Product Name | (R)-1-(2,6-Dichloro-3-Fluorophenyl)Ethanol |
| CAS No. | 330156-50-8 |
| Molecular Formula | C8H7Cl2FO |
| Molecular Weight | 209.05 g/mol |
| Synonyms | (R)-1-(2,6-Dichloro-3-fluorophenyl)ethan-1-ol; (R)-α-(2,6-Dichloro-3-fluorophenyl)ethyl alcohol; (R)-2,6-Dichloro-3-fluoro-α-methylbenzyl alcohol; (R)-1-(2,6-Dichloro-3-fluorophenyl)ethyl alcohol; (R)-1-(2,6-Dichloro-3-fluorophenyl)ethanol; (R)-2,6-Dichloro-3-fluoro-α-phenethyl alcohol; (R)-DCFPE |
| EINECS | Contact for details |
Quality Control
Our production of (R)-1-(2,6-Dichloro-3-Fluorophenyl)Ethanol adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is subjected to comprehensive analytical testing, including chiral HPLC, NMR, and GC-MS. A Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with every shipment, supporting compliance in cGMP and research applications.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorinating agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Enantiomeric Excess (Chiral HPLC) | ≥ 99.0% |
| Melting Point | Contact for details |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals | ≤ 10 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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