Description

Pelitinib is a potent and selective small-molecule inhibitor of the Epidermal Growth Factor Receptor (EGFR) tyrosine kinase. This compound is of significant interest in pharmaceutical research and development for its targeted therapeutic potential. It is primarily utilized by research institutions and pharmaceutical companies engaged in oncology drug discovery and preclinical studies.

Application

• Pharmaceutical Research & Development: As a key reference standard and active pharmaceutical ingredient (API) in the development of novel anti-cancer therapies.
• Oncology Studies: For in vitro and in vivo research targeting EGFR-mutated cancers, including non-small cell lung cancer (NSCLC).
• Biochemical Assays: Used as a selective inhibitor to study EGFR signaling pathways and mechanisms of drug resistance.
• Preclinical Testing: Serves as a critical material for pharmacokinetic, pharmacodynamic, and toxicology evaluations.
• High-Purity Reference Standard: For quality control and analytical method development in pharmaceutical manufacturing.

Basic Information

Product Name	Pelitinib
CAS No.	326894-84-2
Molecular Formula	C₂₄H₂₅ClFN₅O₃
Molecular Weight	485.94 g/mol
Synonyms	EKB-569; WAY-EKB 569; N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-4-quinazolinamine; EKB569; WAY EKB569; Pelitinib (EKB-569)
EINECS	Contact for details

Quality Control

Our Pelitinib is manufactured under strict quality management systems to ensure the highest standards of purity and consistency for research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by advanced analytical techniques including HPLC, NMR, and MS. We are committed to supplying materials that meet the rigorous demands of pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.