Description

Isoconazole is a potent synthetic imidazole derivative widely recognized for its robust antifungal and antibacterial properties. This compound is a critical active pharmaceutical ingredient (API) essential for developing effective topical treatments. It is primarily utilized by pharmaceutical manufacturers and research institutions in the formulation of creams, ointments, and powders for dermatological applications.

Application

• Topical Antifungal Formulations: Primary active ingredient in creams, ointments, and powders for treating cutaneous fungal infections like athlete's foot, ringworm, and candidiasis.
• Dermatological Preparations: Used in combination products for treating mixed infections and inflammatory skin conditions due to its broad-spectrum activity.
• Veterinary Medicine: Incorporated into topical treatments for fungal skin infections in companion and livestock animals.
• Pharmaceutical Research: Serves as a reference standard and key intermediate in R&D for novel antifungal agents and drug delivery systems.
• Cosmeceutical Products: Potential use in specialized personal care products aimed at addressing microbial-related skin concerns.

Basic Information

Product Name	Isoconazole
CAS No.	322764-97-6
Molecular Formula	C18H14Cl4N2O
Molecular Weight	416.13 g/mol
Synonyms	1-[2-(2,4-Dichlorophenyl)-2-[(2,6-dichlorophenyl)methoxy]ethyl]-1H-imidazole; Isoconazole nitrate (salt form); Travogen; Fazol; Gyno-Travogen; Isotral; (RS)-1-[2,4-Dichloro-β-[(2,6-dichlorobenzyl)oxy]phenethyl]imidazole
EINECS	Contact for details

Quality Control

Our Isoconazole is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including identification, purity assay, and impurity profiling via HPLC, to ensure it meets high-grade pharmaceutical standards. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and efficacy.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.