Description

Isoconazole is a potent synthetic imidazole derivative widely recognized for its significant antifungal and antibacterial properties. This compound is a critical active pharmaceutical ingredient (API) essential for developing effective topical treatments. It is primarily utilized by pharmaceutical manufacturers and research institutions in the formulation of creams, ointments, and other dermatological preparations to combat fungal infections.

Application

• Pharmaceutical API: Core active ingredient in topical antifungal creams, ointments, and powders.
• Dermatological Treatments: Formulated for treating cutaneous mycoses, including athlete's foot, ringworm, and candidiasis.
• Veterinary Medicine: Used in topical preparations for fungal skin infections in animals.
• Research & Development: Serves as a reference standard and key intermediate in pharmacological and microbiological studies.
• Cosmeceutical Applications: Incorporated into specialized formulations for dandruff control and scalp health products.

Basic Information

Product Name	Isoconazole
CAS No.	322764-96-5
Molecular Formula	C18H14Cl4N2O
Molecular Weight	416.13 g/mol
Synonyms	1-[2-(2,4-Dichlorophenyl)-2-[(2,6-dichlorophenyl)methoxy]ethyl]-1H-imidazole; Isoconazole Nitrate (salt form); Travogen; Fazol; Gyno-Travogen; (1-[(2RS)-2-(2,4-Dichlorophenyl)-2-[(2,6-dichlorobenzyl)oxy]ethyl]-1H-imidazole)
EINECS	Contact for details

Quality Control

Our Isoconazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via HPLC, to ensure it meets high-grade pharmaceutical standards. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which could affect stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.