Description

4-(1,3-Oxazol-5-Yl)Phenyl Isothiocyanate is a specialized heterocyclic building block featuring a reactive isothiocyanate group. This compound is valued for its role as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists working in medicinal chemistry, where it is used to introduce the thiourea moiety via nucleophilic addition reactions.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new pharmacophores.
• Agrochemical Synthesis: Serves as an intermediate in the development of new herbicides and fungicides with specific modes of action.
• Bioconjugation & Probe Development: The reactive isothiocyanate group allows for labeling proteins, peptides, and other biomolecules for diagnostic and research applications.
• Material Science: Potential use as a monomer or cross-linking agent in the synthesis of specialty polymers with unique properties.

Basic Information

Product Name	4-(1,3-Oxazol-5-Yl)Phenyl Isothiocyanate
CAS No.	321309-41-5
Molecular Formula	C10H6N2OS
Molecular Weight	202.23 g/mol
Synonyms	5-[4-(Isothiocyanato)phenyl]oxazole; 4-(Oxazol-5-yl)phenyl isothiocyanate; 4-(1,3-Oxazol-5-yl)benzenisothiocyanate; 4-(5-Oxazolyl)phenyl isothiocyanate; 321309-41-5; 4-(Oxazol-5-Yl)Phenyl Isothiocyanate; 5-(4-Isothiocyanatophenyl)-1,3-oxazole
EINECS	Contact for details

Quality Control

Every batch of 4-(1,3-Oxazol-5-Yl)Phenyl Isothiocyanate is manufactured and tested under strict quality management systems. We provide comprehensive analytical data including HPLC purity, NMR, and mass spectrometry to ensure identity and consistency for your critical research and development work. Certificates of Analysis (COA) are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.