Description

5-(2-Thienyl)Nicotinoyl Chloride Hydrochloride is a high-purity, reactive chemical intermediate designed for advanced synthesis. This compound is critical for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Serves as a precursor for functional organic materials, including ligands for catalysis and monomers for specialized polymers.
• Chemical Synthesis: Acts as an acylating agent in organic synthesis for introducing the 5-(2-thienyl)nicotinoyl moiety into target molecules.
• Academic & Contract Research: Essential reagent in university laboratories and CROs (Contract Research Organizations) for exploratory chemistry and method development.

Basic Information

Product Name	5-(2-Thienyl)Nicotinoyl Chloride Hydrochloride
CAS No.	321309-36-8
Molecular Formula	C11H7Cl2NOS
Molecular Weight	272.15 g/mol
Synonyms	5-(Thiophen-2-yl)nicotinoyl chloride hydrochloride; 3-Pyridinecarbonyl chloride, 5-(2-thienyl)-, hydrochloride; Nicotinoyl chloride, 5-(2-thienyl)-, hydrochloride; 5-(2-Thienyl)-3-pyridinecarbonyl chloride hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 5-(2-Thienyl)Nicotinoyl Chloride Hydrochloride is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development applications. A detailed Certificate of Analysis (COA) is available for each lot, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.