Description

Methyl P,p-Bis(2,2,2-Trifluoroethyl)Dibromophosphonoacetate is a specialized organophosphorus compound featuring a reactive dibromophosphonoacetate core flanked by trifluoroethyl groups. This unique structure makes it a valuable high-purity building block for advanced chemical synthesis, particularly in the development of novel active ingredients. It is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating complex molecules with specific biological or material properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those requiring phosphorus-containing scaffolds for enhanced bioactivity or as prodrug components.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, insecticides, and fungicides, leveraging its reactive halogen and phosphonate groups.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized phosphonate-based ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of flame-retardant additives, specialty polymers, and surface-modifying agents due to the presence of bromine and phosphorus.
• Chemical Biology Probes: Utilized to develop activity-based probes and molecular tools for studying enzyme mechanisms, particularly those involving phosphorylation.

Basic Information

Product Name	Methyl P,p-Bis(2,2,2-Trifluoroethyl)Dibromophosphonoacetate
CAS No.	318967-86-1
Molecular Formula	C9H11Br2F6O4P
Molecular Weight	491.87 g/mol
Synonyms	Methyl P,P-Bis(2,2,2-trifluoroethyl) Dibromophosphonoacetate; Dibromo(2,2,2-trifluoroethoxy)phosphorylacetic Acid Methyl Ester; Acetic acid, 2-[dibromo(2,2,2-trifluoroethoxy)phosphinyl]-, methyl ester; Methyl 2-[dibromo(2,2,2-trifluoroethoxy)phosphoryl]acetate; Methyl α-(dibromophosphinyl)-α-(2,2,2-trifluoroethoxy)acetate; P,P-Bis(2,2,2-trifluoroethyl) P'-methyl dibromophosphonoacetate
EINECS	Contact for details

Quality Control

Every batch of our Methyl P,p-Bis(2,2,2-Trifluoroethyl)Dibromophosphonoacetate is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.