Description

Inosine 5'-Triphosphate, Trisodium Salt Hydrate, 97 is a high-purity nucleotide analog essential for biochemical research and diagnostic applications. This compound serves as a critical substrate and energy source in enzymatic reactions, particularly those involving polymerases and kinases. It is primarily utilized by researchers and manufacturers in the fields of molecular biology, diagnostics, and pharmaceutical development who require reliable, high-quality nucleotide components for sensitive assays and synthesis.

Application

• Enzymatic Synthesis: As a substrate for RNA polymerases in in vitro transcription and for DNA polymerases in specialized sequencing or labeling applications.
• Biochemical Assays: Used in kinase activity assays, ATP-dependent enzyme studies, and other enzymatic reactions where it can act as a phosphate donor or analog.
• Diagnostic Reagent Manufacturing: A key raw material in the production of reagents for clinical diagnostics, including PCR and other nucleic acid amplification techniques.
• Cell Culture & Metabolism Research: Employed in studies of purine metabolism, nucleotide salvage pathways, and intracellular signaling.
• Pharmaceutical Intermediates: Serves as a building block or intermediate in the research and development of nucleotide-based therapeutics.

Basic Information

Product Name	Inosine 5'-Triphosphate, Trisodium Salt Hydrate, 97
CAS No.	314041-00-4
Molecular Formula	C10H11N4Na3O14P3 · xH2O
Molecular Weight	Approx. 586.10 (anhydrous basis)
Synonyms	ITP Trisodium Salt; Sodium Inosine Triphosphate; 5'-ITP Na3; Inosine-5'-triphosphate trisodium salt; ITP Na3; Inosine triphosphate trisodium salt hydrate; Trisodium inosine 5'-(tetrahydrogen triphosphate)
EINECS	Contact for details

Quality Control

Our Inosine 5'-Triphosphate, Trisodium Salt Hydrate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is tested to confirm identity, potency, and the absence of critical impurities such as nucleases and other nucleotides. A comprehensive Certificate of Analysis (COA) detailing purity (HPLC), water content, and other relevant parameters is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to minimize moisture absorption. For extended storage, consider desiccant use.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/UV)	Conforms
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 10.0%
pH (1% Solution)	6.0 - 8.0
Endotoxin (LAL)	< 10 EU/mg (if specified)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.