Description

3-Pyridinecarbonyl Chloride, 6-Cyano- (9Ci) is a versatile and highly reactive chemical building block, specifically an acyl chloride derivative of a cyano-substituted pyridine. Its core value proposition lies in its ability to efficiently introduce the 6-cyano-nicotinoyl moiety into target molecules, enabling the synthesis of complex heterocyclic compounds. This intermediate is particularly valuable for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system, oncology, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for biological activity.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials, such as novel polymers and small molecules for OLEDs or photovoltaic applications.
• Chemical Biology Probes: Useful for synthesizing labeled compounds or probes for studying biological processes and enzyme inhibition.
• Custom Synthesis and R&D: A critical reagent for contract research organizations (CROs) and fine chemical companies engaged in custom synthesis and process development.

Basic Information

Product Name	3-Pyridinecarbonyl Chloride, 6-Cyano- (9Ci)
CAS No.	313350-44-6
Molecular Formula	C7H3ClN2O
Molecular Weight	166.56 g/mol
Synonyms	6-Cyanonicotinoyl chloride; 6-Cyanopyridine-3-carbonyl chloride; 3-Cyano-6-pyridinecarbonyl chloride; 6-Cyano-3-pyridinecarboxylic acid chloride; 2-Cyano-5-pyridinecarbonyl chloride; 5-(Chlorocarbonyl)-2-cyanopyridine; Nicotinoyl chloride, 6-cyano-; 6-CN-Pyridine-3-COCl
EINECS	Contact for details

Quality Control

Our 3-Pyridinecarbonyl Chloride, 6-Cyano- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed batch-specific data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature and reactivity, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.