Description

Regadenoson is a selective A2A adenosine receptor agonist used as a pharmacological stress agent in myocardial perfusion imaging. This compound is critical for the non-invasive diagnosis of coronary artery disease by inducing coronary vasodilation, mimicking the effects of exercise. It is primarily required by pharmaceutical manufacturers, contract research organizations (CROs), and diagnostic imaging centers for the production of radiopharmaceuticals and clinical diagnostic kits.

Application

• Pharmaceutical Active Ingredient (API): Core component in the manufacture of finished injectable drugs for cardiac stress testing.
• Myocardial Perfusion Imaging (MPI): Used as a vasodilator in pharmacologic stress tests to assess blood flow to the heart muscle.
• Diagnostic Kit Formulation: Incorporated into standardized kits for use with radiopharmaceuticals like Technetium-99m sestamibi or tetrofosmin.
• Clinical Research: Serves as a reference standard and key material in cardiovascular disease research and new diagnostic method development.
• Contract Manufacturing: Supplied to CDMOs for the production of generic and branded regadenoson injection products.
• Hospital & Diagnostic Center Supply: Provided to compounding pharmacies and large healthcare networks for direct clinical use.

Basic Information

Product Name	Regadenoson
CAS No.	313348-27-5
Molecular Formula	C15H18N8O5
Molecular Weight	390.35 g/mol
Synonyms	2-[4-[(Methylamino)carbonyl]-1H-pyrazol-1-yl]adenosine; CVT-3146; Lexiscan; 1-[6-Amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-2-yl]-N-methylpyrazole-4-carboxamide; Regadenosonum; UNII-7LV9FUR4A0
EINECS	Contact for details

Quality Control

Our Regadenoson is manufactured under strict quality management systems. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical applications, with a typical purity of ≥98.0% (by HPLC). We provide comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles, supporting compliance with cGMP and ICH Q3 guidelines for pharmaceutical ingredients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	98.0% - 102.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.