Description

8-n-Benzoylpiperazinylhypoxanthine is a specialized purine derivative and heterocyclic organic compound of significant interest in advanced chemical synthesis. This high-purity intermediate is valued for its role as a key building block in the development of novel pharmaceutical compounds and biochemical research tools. It is primarily utilized by research institutions and pharmaceutical development companies engaged in medicinal chemistry, particularly for the synthesis of potential adenosine receptor ligands and other biologically active molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates targeting neurological and cardiovascular pathways.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies, particularly for adenosine receptor modulators.
• Biochemical Probe Development: Used in the creation of labeled compounds and probes for studying enzyme kinetics and receptor binding assays.
• High-Throughput Screening (HTS): Employed as a reference standard or building block in libraries for drug discovery screening campaigns.
• Academic & Institutional Research: Fundamental research into purine chemistry and the development of new heterocyclic compounds.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client projects.

Basic Information

Product Name	8-n-Benzoylpiperazinylhypoxanthine
CAS No.	312517-56-9
Molecular Formula	C₁₆H₁₆N₆O₂
Molecular Weight	324.34 g/mol
Synonyms	8-(4-Benzoylpiperazin-1-yl)hypoxanthine; 8-(4-Benzoyl-1-piperazinyl)-1H-purin-6-ol; 8-(4-Benzoylpiperazin-1-yl)-1H-purin-6(9H)-one; 8-(N-Benzoylpiperazinyl)hypoxanthine; 8-Benzoylpiperazinylhypoxanthine; BPH; 1H-Purin-6-ol, 8-(4-benzoyl-1-piperazinyl)-
EINECS	Contact for details

Quality Control

Our 8-n-Benzoylpiperazinylhypoxanthine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards for fine chemical intermediates, and custom purity grades or analytical packages can be developed to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.