Description

Pyrazolo[1,5-A]Pyridine-3-Carbonyl Chloride, 4,5,6,7-Tetrahydro- (9Ci) is a versatile and reactive heterocyclic building block, specifically an acid chloride derivative of a tetrahydro-pyrazolopyridine scaffold. Its primary value lies in its role as a key synthetic intermediate for constructing complex molecules in advanced pharmaceutical research and development. This compound is essential for medicinal chemists and process R&D teams working on novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Serves as a monomer or cross-linking agent in the creation of specialty polymers with unique thermal or electronic properties.
• Chemical Biology: Employed as a probe or linker in bioconjugation chemistry for labeling proteins or other biomolecules.
• Academic & Contract Research: A valuable reagent for methodology development and exploring new chemical spaces in organic synthesis laboratories.

Basic Information

Product Name	Pyrazolo[1,5-A]Pyridine-3-Carbonyl Chloride, 4,5,6,7-Tetrahydro- (9Ci)
CAS No.	307307-99-9
Molecular Formula	C9H9ClN2O
Molecular Weight	196.63 g/mol
Synonyms	4,5,6,7-Tetrahydro-1H-pyrazolo[1,5-a]pyridine-3-carbonyl chloride; 4,5,6,7-Tetrahydro-2H-pyrazolo[1,5-a]pyridine-3-carbonyl chloride; 1H-Pyrazolo[1,5-a]pyridine-3-carbonyl chloride, 4,5,6,7-tetrahydro-; Tetrahydro-pyrazolopyridine-3-carbonyl chloride; Pyrazolo[1,5-a]pyridine-3-carbonyl chloride, tetrahydro-; 307307-99-9; 4,5,6,7-Tetrahydro-2H-pyrazolo[1,5-a]pyridine-3-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our production of Pyrazolo[1,5-A]Pyridine-3-Carbonyl Chloride adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We employ advanced analytical techniques including HPLC, NMR, and MS to verify specifications. While produced under controlled conditions suitable for non-GMP R&D use, specific purity grades can be customized upon request to meet your project's exact requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, it must be kept under an inert atmosphere (e.g., nitrogen or argon) and away from moisture, strong bases, and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.