Description

4,6-Dichloro-1H-Indole-2-Carbonyl Chloride is a versatile and highly reactive indole-based building block crucial for advanced organic synthesis. Its value lies in its dual functionality, serving as a key precursor for constructing complex heterocyclic scaffolds found in pharmaceuticals and agrochemicals. This intermediate is primarily needed by research chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical industries for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in oncology and CNS (Central Nervous System) research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides with specific modes of action.
• Material Science Research: Serves as a precursor for creating specialized organic electronic materials and functional dyes.
• Bioconjugation & Probe Development: Employed in the creation of fluorescent probes and biochemical tools for diagnostic and research applications.
• Academic & Contract Research: Essential for synthetic chemistry research in universities and CROs (Contract Research Organizations) exploring new indole chemistry.
• Custom Synthesis: A starting material for the contract manufacturing of proprietary compounds and advanced intermediates.

Basic Information

Product Name	4,6-Dichloro-1H-Indole-2-Carbonyl Chloride
CAS No.	306937-25-7
Molecular Formula	C9H4Cl3NO
Molecular Weight	248.49 g/mol
Synonyms	4,6-Dichloroindole-2-carbonyl chloride; 2-Carbamoyl-4,6-dichloroindole acid chloride; 4,6-Dichloro-1H-indole-2-carboxylic acid chloride; 4,6-Dichloro-2-indolecarbonyl chloride; 4,6-Dichloroindole-2-carboxylic acid chloride; 306937-25-7; 1H-Indole-2-carbonyl chloride, 4,6-dichloro-
EINECS	Contact for details

Quality Control

Our 4,6-Dichloro-1H-Indole-2-Carbonyl Chloride is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.