Description

3-[4-(Trifluoromethoxy)Phenyl]Prop-2-Enoyl Chloride is a high-value, reactive organic intermediate characterized by its trifluoromethoxy phenyl and acid chloride functional groups. This compound is essential for introducing the trifluoromethoxy moiety into target molecules, a modification known to enhance metabolic stability, lipophilicity, and bioavailability. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in areas like kinase inhibitors, anti-inflammatory agents, and CNS-active compounds.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the trifluoromethoxy group improves efficacy and environmental profile.
• Liquid Crystal & OLED Material Precursor: Serves as a critical starting material for synthesizing fluorinated aromatic components used in electronic display technologies.
• Advanced Polymer Modification: Employed to introduce fluorinated side chains into polymers to alter surface properties, chemical resistance, and thermal stability.
• Custom Chemical Synthesis & Contract Research: A vital reagent for custom synthesis houses and R&D laboratories developing proprietary compounds for various industrial applications.

Basic Information

Product Name	3-[4-(Trifluoromethoxy)Phenyl]Prop-2-Enoyl Chloride
CAS No.	306936-02-7
Molecular Formula	C10H6ClF3O2
Molecular Weight	250.60 g/mol
Synonyms	3-[4-(Trifluoromethoxy)phenyl]prop-2-enoyl chloride; (E)-3-[4-(Trifluoromethoxy)phenyl]acryloyl chloride; 4-(Trifluoromethoxy)cinnamoyl chloride; (E)-4-(Trifluoromethoxy)cinnamic acid chloride; 3-[4-(Trifluoromethoxyphenyl)]-2-propenoyl chloride; p-Trifluoromethoxycinnamoyl chloride; 306936-02-7; TFMPAC
EINECS	Contact for details

Quality Control

Our production of 3-[4-(Trifluoromethoxy)Phenyl]Prop-2-Enoyl Chloride adheres to stringent in-process controls and final batch analysis to ensure consistent high purity and reliability. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to support cGMP and ISO standards for traceability and documentation, making it suitable for demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and reactive acid chloride nature, the container must be kept under an inert atmosphere (e.g., nitrogen or argon) and protected from moisture. Keep away from strong bases, oxidizing agents, and alcohols.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.