Description

6-Chloro-2H-1-Benzopyran-3-Carbonyl Chloride is a versatile and highly reactive organic intermediate, specifically a functionalized benzopyran derivative. Its core value lies in its dual reactive sites, the acid chloride and the chloro-substituted aromatic ring, which enable efficient synthesis of complex heterocyclic compounds. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, serving as a key building block for the development of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides, leveraging the benzopyran scaffold for biological activity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced organic materials with specific optical or electronic properties.
• Dye and Pigment Manufacturing: Acts as a key intermediate for synthesizing complex chromophores and functional dyes used in high-performance imaging and coloring applications.
• Chemical Biology Probe Development: Utilized to create tagged or modified molecular probes for studying biological pathways and enzyme functions.

Basic Information

Product Name	6-Chloro-2H-1-Benzopyran-3-Carbonyl Chloride
CAS No.	306935-54-6
Molecular Formula	C10H4Cl2O2
Molecular Weight	229.04 g/mol
Synonyms	6-Chlorochromone-3-carbonyl chloride; 6-Chloro-3-chlorocarbonylchromone; 6-Chloro-2H-chromene-3-carbonyl chloride; 6-Chloro-2H-1-benzopyran-3-carboxylic acid chloride; 3-(Chlorocarbonyl)-6-chloro-2H-chromene; 6-Chloro-2H-1-benzopyran-3-carbonyl chloride; 6-Chloro-3-chlorocarbonyl-2H-chromene
EINECS	Contact for details

Quality Control

Our 6-Chloro-2H-1-Benzopyran-3-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.