Description

Trimethoprim Naphthoate, 98 is a high-purity pharmaceutical intermediate, specifically the naphthoate salt of the antibiotic agent trimethoprim. This compound is critical for ensuring the stability, bioavailability, and precise formulation of active pharmaceutical ingredients (APIs) in finished drug products. It is primarily required by manufacturers in the pharmaceutical and veterinary medicine industries for the development and production of antibacterial formulations.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of finished antibacterial drug formulations.
• Veterinary Medicine Production: Used in the manufacture of antibiotics for treating bacterial infections in livestock and companion animals.
• API (Active Pharmaceutical Ingredient) Synthesis: Serves as a precursor or salt form in the production of trimethoprim-based APIs.
• Research & Development: Employed in laboratory settings for pharmacological studies and the development of new antibacterial agents.
• Formulation Excipient: Can be utilized to modify the physical properties, such as solubility and stability, of final drug products.

Basic Information

Product Name	Trimethoprim Naphthoate, 98
CAS No.	304671-81-6
Molecular Formula	C14H18N4O3 • C11H8O2
Molecular Weight	290.32 (Trimethoprim) + 172.18 (Naphthoic Acid) = 462.50 g/mol (approx.)
Synonyms	Trimethoprim 1-Naphthoate; Trimethoprim Naphthalene-1-carboxylate; 5-[(3,4,5-Trimethoxyphenyl)methyl]-2,4-pyrimidinediamine naphthoate; TMP Naphthoate; Trimethoprim α-Naphthoate; 2,4-Diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine naphthalene-1-carboxylate
EINECS	Contact for details

Quality Control

Our Trimethoprim Naphthoate, 98 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets the specified purity of 98% minimum and complies with relevant standards for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and quality assurance for our B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.