Description

Dasatinib CAS NO 302962-49-8 is a potent, orally bioavailable small molecule tyrosine kinase inhibitor. It matters as a critical active pharmaceutical ingredient (API) for the formulation of targeted cancer therapies, offering a mechanism to combat resistant disease states. Pharmaceutical manufacturers and advanced research institutions require this high-purity compound for the development and production of oncology medications, particularly for the treatment of chronic myeloid leukemia (CML) and acute lymphoblastic leukemia (ALL).

Application

• Primary Active Pharmaceutical Ingredient (API) in targeted oncology drug formulations.
• Research and development of novel tyrosine kinase inhibitor-based therapies.
• Production of generic pharmaceutical products following patent expiry.
• Biochemical research for studying BCR-ABL and SRC family kinase signaling pathways.
• Reference standard for analytical method development and quality control in pharmaceutical labs.
• Pre-clinical studies for evaluating new combination cancer treatment regimens.

Basic Information

Product Name	Dasatinib
CAS No.	302962-49-8
Molecular Formula	C22H26ClN7O2S
Molecular Weight	488.01 g/mol
Synonyms	BMS-354825; Sprycel (Trade Name); N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide; Dasatinib Monohydrate; Dasatinib Anhydrous; Dasatinib (free base)
EINECS	Contact for details

Quality Control

Our Dasatinib is manufactured under strict quality management systems to meet the exacting standards of the pharmaceutical industry. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identification by spectroscopic methods. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment, ensuring full traceability and compliance with cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥98.5%
Related Substances (HPLC)	Total impurities ≤1.5%
Single Maximum Impurity	≤0.5%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.