Description

3,5-Difluorophenyl Isothiocyanate (97%) is a versatile and reactive aromatic isothiocyanate derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to introduce the thiourea pharmacophore, a key structural motif in medicinal chemistry, through reactions with amines. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor for synthesizing thiourea and guanidine derivatives with potential biological activity.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and insecticides.
• Material Science: Used in the modification of polymers and surfaces to impart specific chemical functionalities.
• Chemical Biology: Acts as a reactive handle for bioconjugation and probe development due to its selective reactivity with amines.
• Organic Synthesis: A versatile reagent for constructing heterocyclic compounds and complex molecular architectures.
• Research & Development: Fundamental reagent in academic and industrial R&D for exploring new chemical entities and reaction pathways.

Basic Information

Product Name	3,5-Difluorophenyl Isothiocyanate (97%)
CAS No.	302912-39-6
Molecular Formula	C7H3F2NS
Molecular Weight	171.17 g/mol
Synonyms	1,3-Difluoro-5-isothiocyanatobenzene; 3,5-Difluorophenyl Mustard Oil; 3,5-Difluorobenzene Isothiocyanate; Isothiocyanic Acid 3,5-Difluorophenyl Ester; NSC 405124; 3,5-Difluorophenyl Isosulfocyanate; 3,5-Difluorophenyl Isorhodanate
EINECS	Contact for details

Quality Control

Our 3,5-Difluorophenyl Isothiocyanate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.