Description

((1 1-Dimethyl-2-Pentynyl)Oxy)Trimethylsilane (CAS No. 302912-18-1) is a specialized organosilicon compound featuring a reactive alkynyloxy functional group. This unique structure makes it a valuable silylating agent and protected intermediate in advanced organic synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing silicon-containing moieties or protecting alcohol groups.
• Agrochemical Synthesis: Used in the research and production of novel pesticides and herbicides where the silyl ether group is a crucial synthetic handle.
• Organic Synthesis Reagent: Acts as a versatile silylating agent in laboratory and pilot-scale reactions to protect hydroxyl groups under mild conditions.
• Material Science Research: Employed in the development of specialty silicones, surface modifiers, and hybrid organic-inorganic polymers.
• Cross-Coupling Reactions: Serves as a substrate in Sonogashira and other metal-catalyzed coupling reactions to create extended conjugated systems.

Basic Information

Product Name	((1 1-Dimethyl-2-Pentynyl)Oxy)Trimethylsilane
CAS No.	302912-18-1
Molecular Formula	C₁₀H₂₀OSi
Molecular Weight	184.35 g/mol
Synonyms	Trimethyl((3,3-dimethylbut-1-yn-1-yl)oxy)silane; 1,1-Dimethyl-2-pentynyloxytrimethylsilane; (3,3-Dimethyl-1-butyn-1-yloxy)trimethylsilane; TMS ether of 3,3-dimethyl-1-butyn-1-ol; Silane, trimethyl[(3,3-dimethyl-1-butyn-1-yl)oxy]-; ((3,3-Dimethyl-1-butynyl)oxy)trimethylsilane
EINECS	Contact for details

Quality Control

Our production of ((1 1-Dimethyl-2-Pentynyl)Oxy)Trimethylsilane adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for synthetic applications. Quality is verified through analytical techniques including GC, HPLC, and NMR spectroscopy. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.