Description

3-(6-Amino-9H-Purin-9-Yl)-2,5-Anhydro-3-Deoxy-D-Mannitol is a high-purity nucleoside derivative and a key intermediate in advanced pharmaceutical synthesis. This compound is valued for its role in the development of novel antiviral and anticancer therapeutics, particularly as a precursor for modified nucleoside analogs. It is essential for research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on nucleotide-based drug discovery and process development.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to nucleotide metabolism.
• Antiviral Drug Development: Serves as a precursor for experimental compounds targeting viral polymerases.
• Process Chemistry: Employed in the scale-up and optimization of routes for active pharmaceutical ingredients (APIs).
• Labeled Compound Synthesis: A starting material for producing isotopically labeled (e.g., 13C, 15N) nucleotides for metabolic tracing.
• Academic Research: Utilized in university and institutional labs for studying nucleic acid chemistry and medicinal chemistry.

Basic Information

Product Name	3-(6-Amino-9H-Purin-9-Yl)-2,5-Anhydro-3-Deoxy-D-Mannitol
CAS No.	302790-80-3
Molecular Formula	C11H14N6O4
Molecular Weight	294.26 g/mol
Synonyms	9-(2,5-Anhydro-3-deoxy-D-mannitol-3-yl)adenine; 3-(6-Amino-9H-purin-9-yl)-2,5-anhydro-3-deoxy-D-mannitol; 2,5-Anhydro-3-deoxy-3-(adenin-9-yl)-D-mannitol; 3-Deoxy-3-(adenin-9-yl)-2,5-anhydro-D-mannitol; Adenine 2,5-anhydromannitol derivative; Nucleoside intermediate 302790-80-3; D-Mannitol, 3-(6-amino-9H-purin-9-yl)-2,5-anhydro-3-deoxy-
EINECS	Contact for details

Quality Control

Our 3-(6-Amino-9H-Purin-9-Yl)-2,5-Anhydro-3-Deoxy-D-Mannitol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.