Description

5-Nitrothiophene-2-Carbonyl Chloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. Its value lies in its role as a versatile building block for constructing complex heterocyclic molecules, particularly in pharmaceutical and agrochemical research. This compound is critically needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and material science industries for creating novel active compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting infectious diseases and central nervous system disorders.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging the thiophene scaffold for bioactivity.
• Material Science Research: Serves as a monomer or functionalization agent for creating specialized polymers and conductive materials.
• Dye and Pigment Manufacturing: Intermediate for producing specialized colorants and photographic sensitizers.
• Ligand and Catalyst Development: Building block for creating complex chelating agents and organocatalysts used in asymmetric synthesis.
• Academic and R&D Laboratories: Fundamental reagent for methodological studies and exploring new chemical reactions in heterocyclic chemistry.

Basic Information

Product Name	5-Nitrothiophene-2-Carbonyl Chloride
CAS No.	39978-57-9
Molecular Formula	C5H2ClNO3S
Molecular Weight	191.59 g/mol
Synonyms	2-Nitro-5-thiophenecarbonyl chloride; 5-Nitro-2-thiophenecarbonyl chloride; 2-Thiophenecarbonyl chloride, 5-nitro-; 5-Nitrothiophene-2-carboxylic acid chloride; 5-Nitro-2-thienoyl chloride; 2-Carbonyl chloride-5-nitrothiophene; 5-Nitro-2-thiophenecarboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 5-Nitrothiophene-2-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR, to ensure it meets the high standards required for research and production. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at 2-8°C (refrigerated) or as specified on the label. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.