Description

2H-1,3-Oxazine-3(4H)-Carbonyl Chloride, Dihydro- (9Ci) is a specialized heterocyclic building block and reactive intermediate of significant interest in advanced organic synthesis. Its core value lies in the highly electrophilic carbonyl chloride group, which enables efficient acylation and amidation reactions for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel heterocyclic compounds with potential biological activity.
• Agrochemical Development: Used in the research and production of advanced pesticides and herbicides.
• Peptide Mimetics & Conjugation: Serves as a coupling agent or protecting group reagent in the synthesis of peptide analogs and bioconjugates.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for creating specialty polymers with unique properties.
• Material Science Research: Employed in the development of advanced organic materials and liquid crystals.
• Custom Synthesis & Contract Manufacturing: A critical reagent for CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2H-1,3-Oxazine-3(4H)-Carbonyl Chloride, Dihydro- (9Ci)
CAS No.	39885-57-9
Molecular Formula	C5H6ClNO2
Molecular Weight	147.56 g/mol
Synonyms	Dihydro-2H-1,3-oxazine-3(4H)-carbonyl chloride; 3,4-Dihydro-2H-1,3-oxazine-3-carbonyl chloride; 1,3-Oxazine-3-carbonyl chloride, 3,4-dihydro-; Tetrahydro-1,3-oxazine-3-carbonyl chloride; Oxazine carbonyl chloride; 39885-57-9; Dihydrooxazine carbonyl chloride
EINECS	Contact for details

Quality Control

Our production of 2H-1,3-Oxazine-3(4H)-Carbonyl Chloride, Dihydro- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for your critical syntheses. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP (current Good Manufacturing Practice) standards for applications requiring the highest level of quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.