Description

3,4-Dimethoxycinnamoyl Chloride is a versatile and reactive acid chloride derivative of cinnamic acid, serving as a crucial building block in advanced organic synthesis. Its primary value lies in its ability to efficiently introduce the 3,4-dimethoxycinnamoyl moiety into target molecules, enabling the creation of compounds with enhanced biological activity and specific functional properties. This high-purity intermediate is essential for research and development chemists, particularly in the pharmaceutical and agrochemical sectors, where it is used to synthesize potential drug candidates, active ingredients, and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in neurological and cardiovascular research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators that require specific cinnamate-based structures.
• Peptide & Protein Modification: Acts as an acylating agent for modifying amino acids, peptides, or proteins to alter their properties or create conjugates.
• Material Science & Polymer Chemistry: Employed in the synthesis of specialty monomers, photoactive polymers, and liquid crystals.
• Cosmetic & Personal Care Actives: Intermediate for UV-absorbing agents and skin-conditioning compounds.
• Organic Synthesis & Research: A fundamental reagent for constructing complex natural product analogs and other fine chemicals in academic and industrial R&D labs.

Basic Information

Product Name	3,4-Dimethoxycinnamoyl Chloride
CAS No.	39856-08-1
Molecular Formula	C11H11ClO3
Molecular Weight	226.66 g/mol
Synonyms	3,4-Dimethoxycinnamic Acid Chloride; (E)-3-(3,4-Dimethoxyphenyl)acryloyl Chloride; Cinnamoyl Chloride, 3,4-dimethoxy-; 3,4-Dimethoxy-trans-cinnamoyl Chloride; 3-(3,4-Dimethoxyphenyl)-2-propenoyl Chloride; Veratroylacryloyl Chloride
EINECS	Contact for details

Quality Control

Our 3,4-Dimethoxycinnamoyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at 2-8°C (refrigerated) or as specified on the label. This compound is hygroscopic (moisture-sensitive) and reacts with water, strong bases, and alcohols. Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Solubility	Soluble in common organic solvents (DCM, THF, DMF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.