Description

Benzo[B]Thiophene-2-Carbonyl Chloride is a high-purity, reactive organic intermediate essential for advanced chemical synthesis. This compound is a critical building block for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for its versatile acylating properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those containing the benzothiophene scaffold, which is prevalent in treatments for various diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the benzothiophene moiety contributes to biological activity.
• Material Science Research: Serves as a monomer or functionalization agent in the development of organic semiconductors, conductive polymers, and liquid crystals.
• Dye and Pigment Manufacturing: Employed in the synthesis of specialized heterocyclic dyes and organic pigments.
• Custom Chemical Synthesis: Utilized by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects and scale-up services.

Basic Information

Product Name	Benzo[B]Thiophene-2-Carbonyl Chloride
CAS No.	39827-11-7
Molecular Formula	C9H5ClOS
Molecular Weight	196.65 g/mol
Synonyms	2-Benzothiophenecarbonyl chloride; 2-Benzothienylcarbonyl chloride; Benzothiophene-2-carbonyl chloride; 2-Carboxybenzothiophene chloride; 2-Benzothiophenecarboxylic acid chloride; BTCC; Thianaphthene-2-carbonyl chloride
EINECS	Contact for details

Quality Control

Our Benzo[B]Thiophene-2-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.