Description

8-Aha-Camp CAS NO 39824-30-1 is a high-purity, modified cyclic adenosine monophosphate (cAMP) analog, a key biochemical tool for intracellular signaling research. This compound is specifically engineered to offer enhanced stability and cell permeability, making it invaluable for studying protein kinase A (PKA) pathways and other cAMP-mediated processes. It is essential for researchers and developers in the fields of pharmaceutical discovery, molecular biology, and biochemical assay development who require reliable and potent modulators of cyclic nucleotide signaling.

Application

• Biochemical Research: As a potent and cell-permeable activator of Protein Kinase A (PKA) for studying intracellular signal transduction cascades.
• Pharmaceutical Screening: Used as a reference standard and tool compound in high-throughput screening assays to identify novel drugs targeting cAMP pathways.
• Cell Biology Studies: Investigation of cAMP's role in cellular functions such as metabolism, gene expression, and ion channel regulation.
• Enzyme Kinetics: Serves as a substrate or modulator in enzymatic studies to understand the kinetics and inhibition of phosphodiesterases (PDEs).
• Neuroscience Research: Exploration of cAMP-mediated synaptic plasticity, memory formation, and neuronal excitability.
• Cardiovascular Research: Studying the effects of cAMP on heart muscle contraction, vascular tone, and related therapeutic interventions.

Basic Information

Item	Detail
Product Name	8-Aha-Camp
CAS No.	39824-30-1
Molecular Formula	C₁₆H₂₂N₇O₇P
Molecular Weight	479.37 g/mol
Synonyms	8-(6-Aminohexyl)amino-cAMP; 8-(6-Aminohexylamino)adenosine 3',5'-cyclic monophosphate; 8-AHA-cAMP; 8-AHA-cyclic AMP; 8-(6-Aminohexyl)aminoadenosine cyclic 3',5'-phosphate; N6-(6-Aminohexyl)-cAMP; cAMP, 8-(6-aminohexyl)amino-
EINECS	Contact for details

Quality Control

Every batch of 8-Aha-Camp is manufactured and tested under strict quality management systems to ensure the highest standards of purity and consistency. Our quality control protocols include comprehensive analytical techniques such as HPLC, NMR, and mass spectrometry to verify identity, potency, and purity. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with our rigorous specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.