Description

Endralazine is a potent and selective pharmaceutical compound belonging to the class of vasodilators. Its primary value lies in its targeted mechanism of action, making it a critical intermediate in the research and development of advanced cardiovascular therapeutics. This high-purity material is essential for pharmaceutical manufacturers, R&D laboratories, and academic institutions focused on creating new treatments for hypertension and related conditions.

Application

• Pharmaceutical Active Ingredient (API) Intermediate: A key building block in the synthesis of the final drug substance for antihypertensive medications.
• Research & Development: Used in preclinical and clinical studies to investigate vasodilation mechanisms and cardiovascular pharmacology.
• Reference Standard: Serves as a high-purity standard for analytical method development, validation, and quality control in pharmaceutical analysis.
• Chemical Synthesis: Employed in organic synthesis for the preparation of novel hydrazine derivatives with potential therapeutic activity.
• Academic Research: Utilized in university and institutional labs for pharmacological studies and educational purposes.

Basic Information

Product Name	Endralazine
CAS No.	39715-02-1
Molecular Formula	C13H15N5O
Molecular Weight	257.29 g/mol
Synonyms	Endralazine; 6-Benzoyl-3-hydrazino-5,6,7,8-tetrahydropyrido[4,3-c]pyridazine; (±)-Endralazine; BQ 22-708; SQ 15860; 6-Benzoyl-3-hydrazino-5,6,7,8-tetrahydropyrido[4,3-c]pyridazine; 5,6,7,8-Tetrahydropyrido[4,3-c]pyridazine-3-hydrazine, 6-benzoyl-
EINECS	Contact for details

Quality Control

Our Endralazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical research. Each lot undergoes comprehensive analytical testing, including identification, assay, and impurity profiling via HPLC and other validated methods. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.