Description

4-Pyridineacetyl Chloride Hydrochloride is a versatile and highly reactive acylating agent, primarily used as a key building block in organic synthesis. Its value lies in its ability to efficiently introduce the 4-pyridineacetyl moiety, a crucial structural component for developing compounds with specific biological activity. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who are engaged in the synthesis of active pharmaceutical ingredients (APIs), ligands, and complex organic molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where the pyridine ring structure imparts specific biological activity.
• Ligand and Catalyst Preparation: Serves as a key reagent for constructing complex ligands used in coordination chemistry and catalysis.
• Peptide Modification: Employed to acylate amino groups in peptides and proteins for research and diagnostic applications.
• Material Science Research: Utilized in the synthesis of functionalized polymers and advanced organic materials.
• Chemical Biology Probes: Acts as a building block for creating molecular probes to study enzyme function and biological processes.

Basic Information

Item	Details
Product Name	4-Pyridineacetyl Chloride Hydrochloride
CAS No.	39685-78-4
Molecular Formula	C7H7Cl2NO
Molecular Weight	192.04 g/mol
Synonyms	4-Pyridylacetyl Chloride Hydrochloride; 2-(4-Pyridinyl)acetyl Chloride Hydrochloride; 4-Pyridineacetic Acid Chloride Hydrochloride; Pyridine-4-acetyl Chloride Hydrochloride; (4-Pyridinyl)acetyl Chloride Hydrochloride; 4-Pyridineacetyl Chloride HCl; 2-(Pyridin-4-yl)acetyl Chloride Hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Pyridineacetyl Chloride Hydrochloride is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept in a cool, dry place. For long-term stability, storage at 2-8°C under an inert atmosphere is recommended. Handle and store away from moisture, strong bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.